Top-Rated Med Spa in Tarpon Springs, FL

Feel refreshed, balanced, and confident with provider-led care shaped by medical expertise and aesthetic artistry. Every treatment is personalized with a focus on safety, natural results, and your individual goals.

HCCE License   ·   #6027765     Biomedical Waste License   ·   #52-64-2891709

Medical Director — Paul Russo Jr., MD·License   #  ME138096   Trisha Street MSN, FNP-C Florida License     #     APRN 11024822

Natural, Unrushed Results
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Transparent Pricing
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Trained in Switzerland
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APRN-Led Care
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Natural, Unrushed Results
✦
Transparent Pricing
✦
Trained in Switzerland
✦
APRN-Led Care
✦
Natural, Unrushed Results
✦
Transparent Pricing
✦
Trained in Switzerland
✦
APRN-Led Care
✦
Natural, Unrushed Results
✦
Transparent Pricing
✦
Trained in Switzerland
✦
APRN-Led Care
✦
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Our Philosophy

Natural, Balanced Results Every Single Time

We believe aesthetic medicine should restore, not alter. At our medical aesthetics clinic in Tarpon Springs, we focus on the full picture of your face and your health rather than treating individual areas in isolation. Trish's background as a Switzerland Masterclass graduate under lip filler expert Julie Horne, combined with her Cadaver Safety Training and commitment to ongoing education, means every decision is grounded in both artistry and anatomy. The result is care that feels personal, looks natural, and is built to last.

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Meet Your Provider

Trish Street, MSN, APRN, FNP-C

Trish Street is not your typical injector. Her career began as a professional makeup artist, where she spent 15 years developing a trained eye for facial balance, light, shadow, and symmetry. She later transitioned into emergency nursing, building a strong foundation in clinical care, precision, and patient safety. Today, she brings both of those worlds together at Tranquility Aesthetics and Wellness in Tarpon Springs. As a Florida APRN, Trish practices as an autonomous nurse practitioner within the scope allowed by Florida law, while aesthetics services are provided with the required medical director oversight. She is also the published author of The Longevity Blueprint and a graduate of a Switzerland Masterclass in lip augmentation under Julie Horne.

Why Patients Choose Us

The Reasons Our Patients Stay

From first-time aesthetic patients to long-term wellness members, people choose Tranquility Aesthetics and Wellness in Tarpon Springs because they want care that is honest, skilled, and built around them. Here is what sets us apart from other med spas in the area.
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APRN-led care with medical director oversight
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Switzerland-trained lip specialist using the Julie Horne technique
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Cadaver Safety Training for advanced anatomical precision
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Transparent, tiered pricing with no surprises
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5.0-star rating across 101+ verified Google reviews
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BizRate 2026 "Best Med Spa in Tarpon Springs" award winner
What We Offer

Aesthetic and Wellness Services in Tarpon Springs, FL

Tranquility Aesthetics and Wellness offers a full range of medical aesthetic and wellness services under one roof. Whether you are looking for natural results from cosmetic treatments or a complete metabolic and hormonal reset, our provider-led clinic in Tarpon Springs has a path forward for you.

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Clinician injects a treatment into a patient’s forehead as she lies on a medical bed

Aesthetics & Skin

Refresh your appearance with personalized aesthetic treatments designed to improve skin tone, texture, clarity, and overall confidence.

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Wellness & Regenerative

Support your health from within with wellness and regenerative services focused on energy, balance, recovery, and long-term well-being.

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Body & Beauty

Enhance your natural shape and feel your best with body and beauty treatments tailored to your personal goals and preferences.

Patient Reviews

What Our Patients in Tarpon Springs Are Saying

Tranquility Aesthetics and Wellness holds a perfect 5.0-star rating across 96 or more verified Google reviews. Our patients consistently highlight the natural outcomes, the no-pressure environment, and the level of clinical expertise Trish brings to every appointment. We are proud to be recognized as the Best Med Spa in Tarpon Springs for 2026.
Your Questions, Answered

Frequently Asked Questions About Our Tarpon Springs Med Spa

  • What is the difference between the $50 aesthetic consultation fee and the $149 medical weight loss evaluation fee?

    These are two separate fees for two different types of appointments. The $50 aesthetic consultation fee is a deposit applied directly toward the cost of your treatment when you move forward. The $149 medical weight loss evaluation is a clinical fee that covers a full assessment including BMI measurement, body composition analysis, and GLP-1 education. It is not a deposit but a standalone clinical service.
  • How is Tranquility Aesthetics and Wellness different from other med spas in the Tarpon Springs area?

    All care is led directly by Trish Street, MSN, APRN, FNP-C, a Florida APRN who operates with full clinical autonomy. There is no off-site medical director and no sales coordinator guiding your treatment plan. Trish's background as both an ICU and international flight nurse and a 15-year National Makeup Artist means she brings a level of anatomical precision and artistic judgment that is rare in the local market. The clinic also holds a 5.0-star rating across 96 or more reviews and the BizRate 2026 Best Med Spa in Tarpon Springs award.
  • What neurotoxins do you offer and how is the pricing structured?

    The clinic offers Botox, Dysport, and Daxxify. Pricing is volume-based and fully transparent: 0 to 30 units are priced at $12.50 per unit, 31 to 50 units at $12 per unit, 51 to 70 units at $11.50 per unit, and 70 or more units at $11 per unit. This tiered structure means the more units you need, the lower the per-unit cost. VIP Aesthetic Members also receive locked-in lower rates, which makes regular maintenance more predictable over time.
  • Can the clinic help with hair loss that occurs during GLP-1 weight loss treatment?

    Yes. Hair shedding is a recognized side effect of rapid weight loss during GLP-1 therapy using medications like Semaglutide or Tirzepatide. Tranquility Aesthetics and Wellness specifically offers regenerative hair restoration services to address this. The clinic intentionally pairs its medical weight loss program with hair restoration as a cross-modality solution, recognizing that patients undergoing metabolic changes often need scalp health support alongside their weight loss care.
  • What is the ArqueDerma Artistic Restoration Lift and how does it differ from standard filler?

    The ArqueDerma Artistic Restoration Lift is a specialized filler technique for which Trish Street holds a specific certification. Rather than simply adding volume to individual areas, it takes a holistic approach to facial restoration by considering balance, proportion, and the relationship between facial zones. It is particularly suited for patients who want to address multiple signs of aging in a cohesive way rather than treating isolated concerns.
  • Is financing available for larger treatments like Morpheus8 or dermal fillers?

    Yes. Cherry financing is available for qualifying patients and offers six months interest-free on larger procedures. This makes treatments like Morpheus8 RF Microneedling and comprehensive filler sessions more accessible without requiring the full investment upfront.
  • What is BioTE hormone therapy and who is it appropriate for?

    BioTE is a bioidentical hormone replacement therapy delivered via small pellets placed under the skin. It is available for both men and women. For women, it is often used to address symptoms of perimenopause and menopause including fatigue, mood changes, sleep disruption, and loss of libido. For men, it is part of the testosterone optimization program targeting brain fog, low energy, and loss of muscle mass. Ongoing monitoring is included through the Wellness and Hormone Membership to ensure levels remain properly balanced over time.
  • What are the clinic's hours and how can appointments be booked?

    The clinic is open Monday, Wednesday, and Friday from 10 AM to 6 PM; Tuesday and Thursday from 10 AM to 4 PM; and Saturday from 12 PM to 5 PM. Appointments can be booked online through the Patient Now Essentials portal.
BusinessRate 2026 “Best of” award for Tranquility Aesthetics and Wellness PLLC, Medical Spa, Tarpon Springs, Florida

brands we carry

TRUSTED BRANDS

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